{"id":"W7116861786","doi":"10.1186/s12877-025-06891-9","title":"A cohort study of growth differentiating factor − 15 (GDF-15) and Interleukin-6 (IL-6) as biomarkers of healthy aging in older adults living with HIV","year":2025,"lang":"en","type":"article","venue":"BMC Geriatrics","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; McGill University; McGill University Health Centre; University of Toronto; University Health Network; Toronto General Hospital; St. Joseph’s Healthcare Hamilton; Maple Leaf Medical Clinic; Women's College Hospital; McMaster University","funders":"Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"Cohort; Cohort study; Healthy aging; Body mass index; Human immunodeficiency virus (HIV); Logistic regression; Multivariate analysis; Ageing; Prospective cohort study","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002077841,0.0001654121,0.0004674902,0.0005197778,0.00007340198,0.000009816816,0.00007211811,0.00007401216,0.00001882319],"category_scores_gemma":[0.0001769616,0.0001355926,0.00003672139,0.0008044958,0.000029181,0.00004759063,0.00007393568,0.0001562124,0.000001646658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001222566,"about_ca_system_score_gemma":0.0002323523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001283329,"about_ca_topic_score_gemma":0.0004205241,"domain_scores_codex":[0.9984573,0.00009852664,0.0006630872,0.000339081,0.0002116832,0.0002303574],"domain_scores_gemma":[0.9987982,0.0003364124,0.0003162494,0.0002833534,0.0001662235,0.00009957617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002171049,0.001167194,0.9932225,0.001123386,0.0001423329,0.000003301789,0.00331563,0.000001474381,0.00002686705,0.00002556538,0.00002623027,0.0007283574],"study_design_scores_gemma":[0.004382219,0.0006393672,0.9901292,0.001292794,0.0001737829,0.000005511321,0.002766838,0.0004843298,0.00002999932,0.000008476728,0.000002283928,0.00008516262],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997031,0.0004758363,0.0004837177,0.0001102018,0.00005947406,0.001562085,0.00001211342,0.00002636861,0.0002392265],"genre_scores_gemma":[0.9985679,0.00009554491,0.001126047,0.00003561558,0.00001181959,0.00007561212,0.00001323131,0.00001759846,0.00005660111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004165114,"threshold_uncertainty_score":0.5529306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01010615148798629,"score_gpt":0.2852990052542107,"score_spread":0.2751928537662244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}