{"id":"W7116913778","doi":"10.1007/s12015-025-11038-9","title":"The Broken Cradle: Bone Marrow Stem Cell Niche Remodelling in Diabetes","year":2025,"lang":"en","type":"article","venue":"Stem Cell Reviews and Reports","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; London Health Sciences Centre; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Diabetes Canada; Lawson Health Research Institute","keywords":"Vasculogenesis; Stem cell; Regenerative medicine; Inflammation; Diabetes mellitus; Bone marrow; Regeneration (biology); Tissue repair","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007614637,0.0003212724,0.0007710198,0.0005313015,0.000321726,0.001414815,0.0004520598,0.001096039,0.001536927],"category_scores_gemma":[0.0004890262,0.0001281698,0.0002419383,0.0004308228,0.001180736,0.001550729,0.0008468896,0.002425682,0.0004896031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005283019,"about_ca_system_score_gemma":0.0006139887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005419145,"about_ca_topic_score_gemma":0.0008315555,"domain_scores_codex":[0.9997802,0.0000661224,0.00002089618,0.00003152537,0.00006775633,0.00003346382],"domain_scores_gemma":[0.9998237,0.00007637797,0.00002007699,0.000006924555,0.00003717512,0.00003575474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007525522,0.00006552054,0.001304753,0.006858473,0.0001221029,0.002623166,0.0009982047,0.0008503618,0.08773837,0.05208199,0.03131102,0.8152936],"study_design_scores_gemma":[0.00006197354,0.0007916369,0.006571252,0.003457858,0.0001390139,0.007203947,0.002170962,0.0007302244,0.02639372,0.05222478,0.9001746,0.00008000409],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005276068,0.9826021,0.00169092,0.006647591,0.001838688,0.000007526218,0.00002905763,0.00002996409,0.001878164],"genre_scores_gemma":[0.05984307,0.9259949,0.001595716,0.005215486,0.002903939,0.00001810225,0.00004738991,0.0000230775,0.004358331],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001536927,"threshold_uncertainty_score":0.005141556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01180836834997725,"score_gpt":0.2439518764908926,"score_spread":0.2321435081409153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}