{"id":"W7117100471","doi":"10.1021/acsami.5c19344","title":"Targeted Infection Control and Tissue Integration via pH-Sensitive Smart Coatings on Implant Surfaces","year":2025,"lang":"en","type":"article","venue":"ACS Applied Materials & Interfaces","topic":"Bone Tissue Engineering Materials","field":"Engineering","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Ministério da Ciência, Tecnologia e Inovação; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Coating; Drug delivery; Implant; Biocompatibility; Antimicrobial; Drug; Surface roughness; Soft tissue; Targeted drug delivery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001546387,0.0004199058,0.000181173,0.0002343205,0.00010033,0.0002833761,0.0002356356,0.0003647436,0.000787032],"category_scores_gemma":[0.0001513819,0.0002616634,0.0001728987,0.000104878,0.0002284104,0.000285158,0.0002757504,0.0002800502,0.0002521055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002533036,"about_ca_system_score_gemma":0.000142125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002145669,"about_ca_topic_score_gemma":0.0003248082,"domain_scores_codex":[0.9999015,0.000008372238,0.000006273663,0.00002758925,0.00003739613,0.00001874614],"domain_scores_gemma":[0.9999018,0.00002742671,0.00003374261,0.00001116737,0.00001324532,0.00001271739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001049806,0.000002578083,0.00002310847,0.00001224043,6.962866e-7,0.00001215338,0.000003728122,0.00003309701,0.9991393,0.00001470022,0.00001100311,0.0007368451],"study_design_scores_gemma":[0.000006420097,0.00007837541,0.00146562,0.000002246207,0.000004803902,0.0001083975,0.000007619765,0.001411108,0.9962233,0.00001644258,0.0006702197,0.000005489165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9619107,0.001975495,0.03334458,0.0001382103,0.00005841954,0.00006970372,0.0002294368,0.0005437045,0.001729747],"genre_scores_gemma":[0.9607856,0.001246955,0.03470721,0.00009819745,0.000031568,0.000102565,0.0001680851,0.00005947088,0.002800328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000787032,"threshold_uncertainty_score":0.002632856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004415469281428137,"score_gpt":0.2084922565509127,"score_spread":0.2040767872694846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}