{"id":"W7117120019","doi":"10.1021/acsomega.5c04914","title":"Preparation and Characterization of Chlorin e6-Conjugated Au Nanoparticles as the Radiosensitizer for Enhanced Radiotherapy","year":2025,"lang":"en","type":"article","venue":"ACS Omega","topic":"Radiation Therapy and Dosimetry","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Novelis (Canada)","funders":"Henan Provincial Science and Technology Research Project; National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Radiosensitizer; HeLa; Ionizing radiation; Nanoparticle; Conjugate; U87; Radiation; Nanomedicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002032333,0.0003320068,0.0002230028,0.0002208077,0.0001278707,0.0001568739,0.000221582,0.0003805643,0.0005704924],"category_scores_gemma":[0.0002328986,0.0001686286,0.0001832561,0.0001494352,0.0001644244,0.0001785479,0.0001615734,0.0002713897,0.000333646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002386507,"about_ca_system_score_gemma":0.00009301084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003850962,"about_ca_topic_score_gemma":0.0006451827,"domain_scores_codex":[0.999905,0.00001200057,0.00000771004,0.00002303288,0.00003836126,0.00001388367],"domain_scores_gemma":[0.9998871,0.00002313376,0.00002738891,0.00001376283,0.00003329171,0.00001531751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001035312,0.000003618015,0.0000237803,0.00001473019,8.692847e-7,0.00001077538,0.000008594339,0.00006119573,0.9993794,0.00001913656,0.000008605624,0.0004589949],"study_design_scores_gemma":[0.000001500512,0.00003182264,0.000295005,0.000001114858,0.000001830522,0.00002541944,0.000003362912,0.0006244028,0.9985856,0.000005113968,0.0004229844,0.000001836469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9694547,0.0009336086,0.02752187,0.00006259143,0.00002478051,0.0001348528,0.0002177058,0.0001629456,0.001486966],"genre_scores_gemma":[0.9562759,0.0008153109,0.03780635,0.00006575904,0.000009422201,0.0001577256,0.0003898493,0.00009080209,0.004388843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005704924,"threshold_uncertainty_score":0.001908541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00875772719510864,"score_gpt":0.292467370518578,"score_spread":0.2837096433234693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}