{"id":"W7117157474","doi":"10.1016/j.neuro.2025.103371","title":"Power calculations for larval zebrafish in light-dark transition test for developmental neurotoxicity","year":2025,"lang":"en","type":"article","venue":"NeuroToxicology","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Institute of Environmental Health Sciences; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Zebrafish; Sample size determination; Analysis of variance; Statistical power; Sample (material); Autism; Statistical hypothesis testing; Repeated measures design; Neurotoxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03626718,0.001135407,0.00154924,0.002127632,0.0006546638,0.0009072224,0.001643424,0.001640349,0.00895435],"category_scores_gemma":[0.09162551,0.0005126489,0.002520822,0.001583432,0.001233682,0.001027555,0.001256492,0.002264735,0.001345787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008929265,"about_ca_system_score_gemma":0.0008949319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000705839,"about_ca_topic_score_gemma":0.0007863461,"domain_scores_codex":[0.9824301,0.008308097,0.001511985,0.001783137,0.005554484,0.0004122309],"domain_scores_gemma":[0.938226,0.04976736,0.003854803,0.003122228,0.004689257,0.0003403377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.02138217,0.002261214,0.08926055,0.007761152,0.005900922,0.002979323,0.003076444,0.05974519,0.1337943,0.03465475,0.04330233,0.5958817],"study_design_scores_gemma":[0.004755056,0.04727372,0.2199415,0.00412656,0.007338407,0.004532622,0.001630334,0.2573633,0.2194256,0.06500781,0.1678421,0.0007629046],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1802884,0.005558578,0.7709952,0.0008740164,0.001158286,0.01476171,0.005400697,0.002314481,0.0186486],"genre_scores_gemma":[0.5457971,0.00136677,0.391122,0.001092485,0.0001683196,0.04915372,0.003100116,0.001019089,0.007180328],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.03626718,"threshold_uncertainty_score":0.1918014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01260419783214517,"score_gpt":0.3077161573187269,"score_spread":0.2951119594865817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}