{"id":"W7117158178","doi":"10.1002/alz70855_103920","title":"Transcriptomic and epigenetic analysis of various cell types affected by amyloid‐beta oligomers in the hippocampus of mice during aging","year":2025,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Neurodegeneration; Hippocampus; Transcriptome; Epigenetics; Cell type; Cell; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001036817,0.0002258115,0.0002792559,0.0004213017,0.0002330563,0.0002514374,0.0001515519,0.000250867,0.001112807],"category_scores_gemma":[0.00007817012,0.0001599215,0.0003065019,0.0002688781,0.0002339051,0.0001633977,0.0001886006,0.000486547,0.000235502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002138113,"about_ca_system_score_gemma":0.0001760389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001082948,"about_ca_topic_score_gemma":0.002659091,"domain_scores_codex":[0.9998937,0.000004028806,0.000004357553,0.00004350865,0.00003086061,0.00002355085],"domain_scores_gemma":[0.9999126,0.000008059697,0.00002941153,0.000006573749,0.00002447373,0.00001881688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001719951,0.0000129361,0.002058078,0.00004855927,0.00001919109,0.00005290256,0.00006801146,0.00006340961,0.9952587,0.00006860596,0.0001204575,0.00205712],"study_design_scores_gemma":[0.00004081454,0.0005014802,0.2649407,0.00004670987,0.0002537593,0.0006617627,0.000533629,0.002365991,0.7226577,0.0005472985,0.007403147,0.00004698321],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781172,0.001693821,0.007298034,0.0001195622,0.00006076731,0.00004086188,0.01062123,0.0001880012,0.001860445],"genre_scores_gemma":[0.9715186,0.002180448,0.008899252,0.000399907,0.00002356352,0.0002920101,0.008954115,0.0001820715,0.00755013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001112807,"threshold_uncertainty_score":0.003722727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009584429458256105,"score_gpt":0.2691140900727709,"score_spread":0.2595296606145148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}