{"id":"W7117253610","doi":"10.1620/tjem.2025.j157","title":"<i>KRAS</i> and <i>MET</i> Co-Mutation in One Lesion and <i>EGFR</i> Mutation in Another Lesion of Early-Stage Synchronous Multiple Lung Adenocarcinomas: A Case Report","year":2025,"lang":"en","type":"article","venue":"The Tohoku Journal of Experimental Medicine","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Aging","funders":"","keywords":"Lesion; Lung; Mutation; Computed tomography; Order (exchange)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001981234,0.0007998082,0.001698268,0.00142571,0.0004056899,0.00006527358,0.000291414,0.0003697006,0.0002409156],"category_scores_gemma":[0.0006062278,0.0006085765,0.0002426915,0.000995209,0.0007814432,0.0007499575,0.0001665305,0.0005750856,0.000007009142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001538177,"about_ca_system_score_gemma":0.0006068405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003228854,"about_ca_topic_score_gemma":0.0005959843,"domain_scores_codex":[0.9939178,0.0004985252,0.002578319,0.0008229568,0.001368021,0.0008144035],"domain_scores_gemma":[0.9959878,0.0007478068,0.001597004,0.000746185,0.0004373794,0.0004837689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002986689,0.002022504,0.0105346,0.0004507261,0.0007897739,0.01225634,0.02221015,0.0001901138,0.9402794,0.00104391,0.001825473,0.005410301],"study_design_scores_gemma":[0.1169043,0.02159421,0.4668127,0.0192867,0.00663754,0.05667659,0.01861426,0.008156878,0.2702665,0.000647535,0.01154409,0.002858776],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9295608,0.06269568,0.0008540278,0.001449363,0.0006361365,0.002208283,0.00005463031,0.00005566368,0.002485407],"genre_scores_gemma":[0.9940405,0.001631646,0.00140671,0.0003728225,0.0004488805,0.0001427741,0.0001518361,0.0001222277,0.001682603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.670013,"threshold_uncertainty_score":0.9996365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02510014679193438,"score_gpt":0.3300880270358333,"score_spread":0.3049878802438989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}