{"id":"W7117298083","doi":"10.1002/alz70859_105733","title":"Double blind clinical trial of lemborexant for AD prevention: Protocol for a randomized controlled clinical trial","year":2025,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Sleep and related disorders","field":"Psychology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; University of Toronto; Institut Universitaire de Gériatrie de Montréal; Alzheimer Society of Canada; Université de Montréal; Concordia University; Hôpital du Sacré-Cœur de Montréal; McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Clinical trial; Double blind; Protocol (science); Randomized controlled trial; Psychological intervention","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02291851,0.00919773,0.01625651,0.002069239,0.004277642,0.003762322,0.004105768,0.007906203,0.08543956],"category_scores_gemma":[0.02236963,0.003203403,0.005113121,0.003090275,0.004600032,0.003802303,0.002014705,0.009257931,0.01709483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004136788,"about_ca_system_score_gemma":0.0129108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002157514,"about_ca_topic_score_gemma":0.004661725,"domain_scores_codex":[0.9847093,0.007858026,0.001595891,0.002019077,0.001856316,0.001961292],"domain_scores_gemma":[0.9893672,0.002057201,0.00223528,0.001555045,0.002616741,0.002168599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9626729,0.008397967,0.000287934,0.005920496,0.001171507,0.0000957832,0.0001037871,0.0007651082,0.001183541,0.001326305,0.007587159,0.01048751],"study_design_scores_gemma":[0.9765134,0.01241934,0.0005096319,0.0005090454,0.0003422679,0.0000202399,0.00002545235,0.000713225,0.0002063268,0.0008777425,0.007825419,0.0000379244],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.002726737,0.000441069,0.001391582,0.0002432541,0.0006344147,0.9922138,0.001129664,0.0001654564,0.001054029],"genre_scores_gemma":[0.003296219,0.0001947123,0.001665752,0.0002482438,0.0001161502,0.993534,0.000215196,0.000009141194,0.0007205977],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.08543956,"threshold_uncertainty_score":0.2858238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1595671373158927,"score_gpt":0.502999994394974,"score_spread":0.3434328570790813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}