{"id":"W7117368346","doi":"10.1002/ange.202522762","title":"A Biocatalytic Platform for the Synthesis of Organofunctional Silanes and Siloxanes","year":2025,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dow Chemical (Canada)","funders":"","keywords":"Silanes; Cyclopropanation; Enantioselective synthesis; Carbene; Diazo; Biocatalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006843165,0.0001161771,0.0001576745,0.00003784626,0.0001074907,0.00001817232,0.000120338,0.00008612818,0.0002040819],"category_scores_gemma":[0.0002114498,0.00008311001,0.00006861219,0.0001011147,0.00008033497,0.00004629901,0.00004753564,0.0000641365,0.000003080877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003725371,"about_ca_system_score_gemma":0.00005606634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003102938,"about_ca_topic_score_gemma":0.00001103432,"domain_scores_codex":[0.9994228,0.000001236938,0.0001619314,0.0001796494,0.0001051506,0.00012916],"domain_scores_gemma":[0.998889,0.0007092845,0.00007166611,0.0002253338,0.00007825971,0.00002645339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007870447,0.00002609271,0.0003003416,0.0006342746,0.0001147359,5.830433e-7,0.00009920608,0.000001472135,0.9903376,0.0006503789,0.0007627337,0.006993936],"study_design_scores_gemma":[0.0002696095,0.000006765878,0.00008091334,0.00006710209,0.0001480986,0.0000110822,0.001008521,0.00001839272,0.9816613,0.000641602,0.01600235,0.00008424126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9593161,0.005210192,0.0006254737,0.001408253,0.0003328907,0.0004034826,0.0002035887,0.0001831923,0.03231688],"genre_scores_gemma":[0.9966959,0.0001527314,0.0001823235,0.00005608137,0.00009375311,0.0001006591,0.00002700455,0.0000137677,0.00267775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03737988,"threshold_uncertainty_score":0.3389128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01508549584051767,"score_gpt":0.2372606228800171,"score_spread":0.2221751270394994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}