{"id":"W7117422237","doi":"10.1016/j.ctrv.2025.103073","title":"Targeted therapies in optic pathway gliomas","year":2025,"lang":"en","type":"article","venue":"Cancer Treatment Reviews","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministero della Salute","keywords":"Targeted therapy; Disease; Disease control; Radiation therapy; Glioma; MEDLINE","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007797203,0.0001921681,0.0006004716,0.0001329391,0.00003666463,0.00001592469,0.00004950404,0.00004082499,0.0002795994],"category_scores_gemma":[0.00001995141,0.0001183147,0.000175053,0.0004024082,0.00002939186,0.000041435,0.00001301231,0.00005319441,0.00004804896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002451888,"about_ca_system_score_gemma":0.0001490724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001273152,"about_ca_topic_score_gemma":0.00005269724,"domain_scores_codex":[0.9990495,0.00007698126,0.0003481816,0.0002677826,0.0000705775,0.0001869584],"domain_scores_gemma":[0.9994922,0.00003483074,0.00006465428,0.0003314218,0.00001922897,0.00005762485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002910937,0.00117246,0.1452183,0.001038961,0.0003363694,0.0009528346,0.0006323322,0.000003080596,0.04000905,0.001990597,0.009472989,0.7988819],"study_design_scores_gemma":[0.00228504,0.0004320612,0.03368565,0.001411514,0.0001585661,0.00002676526,0.00004002581,0.00001613289,0.02119793,0.00006541901,0.9405396,0.0001412761],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6644073,0.3284213,0.000003657793,0.001238096,0.0001710061,0.0009785426,0.000008762299,0.00003512581,0.004736327],"genre_scores_gemma":[0.8950043,0.09386168,0.0007481946,0.001213267,0.0001054336,0.001736117,0.00003508891,0.00002632014,0.00726965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9310666,"threshold_uncertainty_score":0.4824732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04199492782811227,"score_gpt":0.3349559020713119,"score_spread":0.2929609742431997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}