{"id":"W7117482769","doi":"10.1002/glia.70127","title":"Acute Intermittent Hypoxia Exerts Beneficial Effects and Promotes Repair in Male Mice in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis","year":2025,"lang":"en","type":"article","venue":"Glia","topic":"High Altitude and Hypoxia","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; University of Saskatchewan; Cameco (Canada)","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society of Canada","keywords":"Experimental autoimmune encephalomyelitis; Multiple sclerosis; Remyelination; Immune system; Hypoxia (environmental); Encephalomyelitis; Disease; Inflammation; Glatiramer acetate","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118793,0.0001190653,0.0001613201,0.00005721532,0.00003623368,0.000009965373,0.0001590916,0.0000967663,0.000002782339],"category_scores_gemma":[0.00003341054,0.00009926138,0.00006290737,0.00008803072,0.0000660987,0.000005943585,0.0001393033,0.00007452187,8.613006e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001349481,"about_ca_system_score_gemma":0.00003445993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001756033,"about_ca_topic_score_gemma":0.0002368993,"domain_scores_codex":[0.9992404,0.00004940599,0.0002070077,0.0002555375,0.00007363355,0.0001739906],"domain_scores_gemma":[0.9996889,0.00001879844,0.00003880025,0.000217388,0.00001785411,0.00001826229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000994103,0.0001588415,0.007368802,0.00004736018,0.00002935685,0.00000794979,0.0005607178,0.0000333085,0.9902259,0.00006391996,0.0002185247,0.001185918],"study_design_scores_gemma":[0.001630631,0.0002690664,0.2218079,0.0002016342,0.00002892915,0.000008232862,0.0002372994,0.003536486,0.7717763,0.00007439745,0.0002488672,0.0001802511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969876,0.002264365,0.0000457743,0.00008165411,0.0000659969,0.0003237737,0.0000231868,0.000007014316,0.0002006204],"genre_scores_gemma":[0.9987053,0.0001400358,0.0007012251,0.0001666874,0.00001894742,0.0000820358,0.00002131207,0.000007033378,0.0001573791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2184496,"threshold_uncertainty_score":0.4047762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213272305838417,"score_gpt":0.2396684234905045,"score_spread":0.2275357004321203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}