{"id":"W7117539649","doi":"10.31579/2578-8949/198","title":"Human Breast Milk–Derived HAMLET Complex: A Natural Anti-Cancer Agent with Selective Cytotoxicity Toward Tumor Cells","year":2025,"lang":"","type":"article","venue":"Dermatology and Dermatitis","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Calgary","keywords":"HAMLET (protein complex); Cytotoxicity; Breast cancer; Apoptosis; Biomarker; Adverse effect; Immune system; Breast tumor; Cancer; Chemotherapy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0002114852,0.0008019313,0.001553483,0.0006147525,0.00229492,0.0003066032,0.0004777407,0.0004435039,0.0004557766],"category_scores_gemma":[0.00003398596,0.000748164,0.0001946039,0.0008210237,0.001855136,0.0004914578,0.0002993059,0.001718201,0.00008601594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003588965,"about_ca_system_score_gemma":0.0006112814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001532831,"about_ca_topic_score_gemma":0.001780655,"domain_scores_codex":[0.9944202,0.001126901,0.001011787,0.001083144,0.0005003204,0.001857654],"domain_scores_gemma":[0.997781,0.0002635292,0.0004097346,0.0005111097,0.0004756426,0.000559011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.002324843,0.002222506,0.173788,0.01452903,0.002991759,0.004290923,0.01340895,0.00008646884,0.2839238,0.003094981,0.4944124,0.004926323],"study_design_scores_gemma":[0.00734587,0.0003137267,0.5536634,0.001444037,0.0002946873,0.005758296,0.001450501,0.004668396,0.4192183,0.0005430926,0.004176581,0.001123085],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9417402,0.006317728,0.001068149,0.04505806,0.0009503162,0.001958621,0.0009008791,0.0001850663,0.001820968],"genre_scores_gemma":[0.9824902,0.0009598627,0.0008131257,0.01513858,0.0001101476,0.0001561042,0.0001423037,0.00005419739,0.0001354276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4902358,"threshold_uncertainty_score":0.9994969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01925778056894625,"score_gpt":0.3073852241072931,"score_spread":0.2881274435383469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}