{"id":"W7117542129","doi":"10.1016/j.immuni.2025.12.001","title":"From host to population: Bridging the viral immuno-evolutionary gap","year":2025,"lang":"en","type":"article","venue":"Immunity","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; McGill University; National Science Foundation","keywords":"Immune system; Identification (biology); Population; Acquired immune system; Viral evolution; Innate immune system; Host (biology); Bridging (networking); Viral pathogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002144153,0.0003575108,0.0007657172,0.0007210771,0.0009422986,0.002870873,0.001068213,0.001848756,0.003608817],"category_scores_gemma":[0.003872583,0.0002284261,0.0002081405,0.0005418006,0.003969445,0.006529957,0.003092276,0.001882529,0.000349723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001380508,"about_ca_system_score_gemma":0.0007952209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006104794,"about_ca_topic_score_gemma":0.0007826971,"domain_scores_codex":[0.9991961,0.0003318029,0.000028187,0.0001829974,0.0001316483,0.0001292935],"domain_scores_gemma":[0.9981482,0.001060499,0.0001774494,0.0002131642,0.0001579249,0.0002428774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002752256,0.0001385598,0.031021,0.000601478,0.0001889089,0.001007147,0.003112775,0.0124162,0.04906439,0.7631534,0.002068067,0.1369527],"study_design_scores_gemma":[0.00005035079,0.000407572,0.040001,0.0002148545,0.00009759833,0.002275793,0.006377313,0.04094682,0.00724174,0.8599039,0.04237914,0.0001039074],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.81849,0.01531778,0.09926272,0.02802963,0.0003237167,0.00003507911,0.0001669003,0.0001607429,0.03821336],"genre_scores_gemma":[0.9929969,0.002365309,0.002673206,0.0008083695,0.0001178227,0.00001144085,0.00002360392,0.00002054252,0.0009828745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003608817,"threshold_uncertainty_score":0.01207274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007401846419784436,"score_gpt":0.2664673892799641,"score_spread":0.2590655428601796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}