{"id":"W7117724648","doi":"10.6084/m9.figshare.30969315","title":"Additional file 3 of Mitochondrial and lysosomal dysfunctions might be involved in the pathogenesis of the CACNA1A-related neurodevelopmental disorders according to in vitro studies","year":2025,"lang":"","type":"article","venue":"Figshare","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pathogenesis; In vitro; Mitochondrion; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001323247,0.001318659,0.001478227,0.002348664,0.001059681,0.002015973,0.002130457,0.001952276,0.9050051],"category_scores_gemma":[0.02092037,0.0006554417,0.001458347,0.003111232,0.0003219392,0.00214537,0.001211238,0.001130359,0.2505967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001089651,"about_ca_system_score_gemma":0.001759356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005520326,"about_ca_topic_score_gemma":0.007708093,"domain_scores_codex":[0.9993643,0.0000778705,0.0001228215,0.0001505475,0.0001668129,0.0001176696],"domain_scores_gemma":[0.9816082,0.01323161,0.001023984,0.0009535963,0.002579486,0.000603091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007131827,0.0001061567,0.002401277,0.004659654,0.0000691138,0.0002491613,0.00007523707,0.0003229594,0.00059661,0.0009712524,0.9796608,0.01017459],"study_design_scores_gemma":[0.005996834,0.0004696624,0.03902115,0.006561063,0.0003261115,0.002017032,0.0005447117,0.001844784,0.003206776,0.01717212,0.9225652,0.0002745372],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"other","genre_scores_codex":[0.0002446635,0.00005512345,0.0002981267,0.0001725396,0.00008320496,0.00005764851,0.9976611,0.0004179112,0.001009665],"genre_scores_gemma":[0.008043685,0.0003503856,0.00344942,0.0008236108,0.0002005427,0.0007354631,0.9740354,0.00120416,0.01115742],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.9050051,"threshold_uncertainty_score":0.1354986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01835017048844569,"score_gpt":0.245296362152298,"score_spread":0.2269461916638523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}