{"id":"W7117754475","doi":"10.3390/v18010054","title":"Expanding Horizons: Host Range Evolution and Treatment Strategies for Highly Pathogenic Avian Influenza H5N1 and H7N9","year":2025,"lang":"en","type":"article","venue":"Viruses","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Ottawa","keywords":"Influenza A virus subtype H5N1; Reassortment; Highly pathogenic; Influenza A virus; Pandemic; Transmission (telecommunications); Clade; Host (biology)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002126832,0.0002946884,0.0003534342,0.0004451611,0.0004533996,0.001462873,0.000836048,0.001289514,0.006738584],"category_scores_gemma":[0.002015401,0.0001057691,0.0004211778,0.0002027949,0.0004563779,0.00147629,0.0007492558,0.001178152,0.0008701013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006597649,"about_ca_system_score_gemma":0.001448571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001394436,"about_ca_topic_score_gemma":0.003849199,"domain_scores_codex":[0.9995562,0.0002093654,0.0000181178,0.00004869315,0.00009224918,0.00007532247],"domain_scores_gemma":[0.9994636,0.0001762559,0.00009566041,0.00002554575,0.00009549179,0.0001434883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005338127,0.000942412,0.0114016,0.001013833,0.00008890178,0.0003283521,0.0004090129,0.001207134,0.01130763,0.006668248,0.02342019,0.9426787],"study_design_scores_gemma":[0.0005819043,0.01312078,0.07229493,0.006398339,0.0008396101,0.003763442,0.00984111,0.01249715,0.01630769,0.04197894,0.8221933,0.0001828265],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1419583,0.630783,0.02241046,0.1444945,0.002629334,0.0003552689,0.0003803585,0.0002566764,0.05673213],"genre_scores_gemma":[0.705847,0.2294576,0.02393443,0.0238435,0.003077521,0.0003470411,0.0004240531,0.00004990124,0.01301898],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006738584,"threshold_uncertainty_score":0.02254277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09112684516675384,"score_gpt":0.393831007523415,"score_spread":0.3027041623566611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}