{"id":"W7118012597","doi":"10.1007/978-3-032-10050-4_25","title":"Liver Function Assessment","year":2025,"lang":"en","type":"book-chapter","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Health; Alberta Health Services","funders":"","keywords":"Drug; Liver function tests; Liver function; Liver toxicity; Multitude; Human liver; Liver dysfunction; Liver damage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0005647854,0.0004282675,0.0003979942,0.0002799173,0.0003671806,0.00003127951,0.0002055985,0.001886684,0.02842773],"category_scores_gemma":[0.00001467011,0.0004311641,0.0002530471,0.00005043287,0.0001041007,0.0001027275,0.0001265241,0.002652369,0.001764065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000312106,"about_ca_system_score_gemma":0.0002742421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000353845,"about_ca_topic_score_gemma":0.000075545,"domain_scores_codex":[0.9984039,0.0001431841,0.0004052778,0.0005127439,0.0002143004,0.0003205948],"domain_scores_gemma":[0.9989796,0.0002298596,0.0002015498,0.0002907072,0.0001422474,0.0001560685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001694172,0.0001017485,0.00003989481,0.0002102503,0.0006027273,0.00004309617,0.00003776091,0.00003109048,0.0006670591,0.593597,0.09285384,0.3116461],"study_design_scores_gemma":[0.0005207943,0.0001295008,0.00007028046,0.00006233285,0.0004521804,0.000009803252,0.000005812675,0.0009030809,0.001472604,0.0194152,0.9765449,0.0004135346],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.00005017584,0.0004145399,0.002723612,0.0004417032,0.004797898,0.000861653,0.00007438954,0.0003198211,0.9903162],"genre_scores_gemma":[0.01111526,0.000828966,0.0002300447,0.004397658,0.0007247975,0.00007699298,0.0001333292,0.00004089609,0.982452],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.883691,"threshold_uncertainty_score":0.999814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1510697689413712,"score_gpt":0.4287318690435475,"score_spread":0.2776621001021763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}