{"id":"W7118125596","doi":"10.1210/clinem/dgaf699","title":"Insulin Levels Early in Perimenopause Inform Vasomotor Symptom Incidence Across the Menopausal Transition","year":2025,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Menopause: Health Impacts and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Nursing Research; Office of Research on Women's Health; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Department of Health and Human Services, State Government of Victoria","keywords":"Vasomotor; Incidence (geometry); Insulin; Menopause; Insulin resistance; Pancreatic hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006103724,0.000155714,0.0001713931,0.0003337401,0.0002186807,0.0006343304,0.0001805298,0.0002885355,0.001579745],"category_scores_gemma":[0.001623675,0.0001939117,0.0003259149,0.0006025743,0.0001560663,0.000281279,0.0003014412,0.0004242846,0.0001695269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001551212,"about_ca_system_score_gemma":0.0002613273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003611395,"about_ca_topic_score_gemma":0.005729369,"domain_scores_codex":[0.9998678,0.00004734291,0.00001105313,0.00003223685,0.00001497992,0.00002653887],"domain_scores_gemma":[0.9991704,0.0001845501,0.000394114,0.00005995499,0.00008858077,0.0001023206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001351737,0.00001357665,0.9979811,0.00001071224,0.00003714279,0.0000162598,0.00004964896,0.00002751862,0.0002706088,0.00001322064,0.00005021768,0.001394829],"study_design_scores_gemma":[0.000001766697,0.00003503488,0.9995636,0.000005047845,0.00001720025,0.00003270001,0.00006512303,0.00009642088,0.0000479187,0.00002413874,0.0001097548,0.000001199811],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997593,0.0008639809,0.0002924436,0.0001073472,0.00001054405,0.000006988647,0.0005567409,0.000006065475,0.0005627095],"genre_scores_gemma":[0.9990049,0.000237402,0.0001818527,0.00003510249,0.000007513945,0.000004816608,0.0003370209,0.00000165044,0.0001896537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003611395,"threshold_uncertainty_score":0.00718075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06871804445640373,"score_gpt":0.4384989167385955,"score_spread":0.3697808722821918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}