{"id":"W7119512736","doi":"10.1002/alz70856_106914","title":"Data‐Driven Characterization of Heterogeneous Brain Atrophy and White Matter Hyperintensity Progression in Frontotemporal Dementia","year":2025,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Frontotemporal dementia; Primary progressive aphasia; Atrophy; Frontotemporal lobar degeneration; Semantic dementia; Hyperintensity; Dementia; Aphasia; Neuroimaging","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003963077,0.0004521456,0.0004222902,0.001002996,0.0002751531,0.0008222712,0.0006461851,0.0004295298,0.0004175386],"category_scores_gemma":[0.008347718,0.0002573188,0.0009810013,0.0005266658,0.0002774807,0.0004030813,0.0005662849,0.0005355138,0.0001412347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005161343,"about_ca_system_score_gemma":0.0006276802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007730149,"about_ca_topic_score_gemma":0.01377158,"domain_scores_codex":[0.9992551,0.0003798441,0.00004844983,0.0001973935,0.00007368669,0.0000454594],"domain_scores_gemma":[0.9972118,0.001540344,0.0004022774,0.0004150316,0.0003455886,0.00008497872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000880953,0.0002500193,0.8844429,0.0002542134,0.00160055,0.0002897659,0.0004174122,0.05124328,0.00991797,0.0009107409,0.001879838,0.04791237],"study_design_scores_gemma":[0.0000555975,0.0002827405,0.5709733,0.00009261254,0.000607385,0.0005471261,0.0002815323,0.4135016,0.006048494,0.005135776,0.002413605,0.00006028873],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792676,0.0004772866,0.01712908,0.0001390167,0.00001075801,0.00003541906,0.00247937,0.0001627335,0.0002986823],"genre_scores_gemma":[0.9889727,0.00006556844,0.007757487,0.00003573261,0.000007607193,0.00003718911,0.002960622,0.0000189012,0.0001441193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007730149,"threshold_uncertainty_score":0.02095902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02546146155760146,"score_gpt":0.31722161098871,"score_spread":0.2917601494311085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}