{"id":"W7125212277","doi":"10.1098/rsbm.2025.0021","title":"Christopher John Marshall","year":2025,"lang":"en","type":"article","venue":"Biographical Memoirs of Fellows of the Royal Society","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Francis Crick Institute","keywords":"Rigour; Passion; Biography; Rest (music); Bench to bedside; Cancer; Identification (biology)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001225769,0.00067783,0.0003808046,0.001189021,0.00250715,0.004507654,0.001148635,0.002240672,0.2097777],"category_scores_gemma":[0.007209317,0.0002929232,0.0003397214,0.0005655438,0.001251174,0.002944696,0.002915833,0.004617587,0.09413631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002755158,"about_ca_system_score_gemma":0.004849364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007955783,"about_ca_topic_score_gemma":0.01115039,"domain_scores_codex":[0.9984429,0.0001709329,0.00005636921,0.0003318887,0.0007756953,0.0002221982],"domain_scores_gemma":[0.9961892,0.0003800482,0.0001420271,0.0002190869,0.001567316,0.001502326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007012489,0.000007365781,0.00008525218,0.00002721245,0.000001065583,0.00008281417,0.0000854024,0.00002319556,0.000111466,0.00847121,0.9690235,0.02207453],"study_design_scores_gemma":[0.000001001591,0.000002018745,0.00005740077,0.00003167077,4.718692e-7,0.0001063839,0.00006432364,0.00001629015,0.00005031464,0.0009706345,0.9986967,0.000002772599],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.001659077,0.02018059,0.003331451,0.2728016,0.1053386,0.0001103564,0.0007931188,0.0009788445,0.5948064],"genre_scores_gemma":[0.00873902,0.007714005,0.001049251,0.02632268,0.007036858,0.00004446986,0.0002175651,0.0003458144,0.9485304],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.2097777,"threshold_uncertainty_score":0.7017763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00519449700143627,"score_gpt":0.217008585054037,"score_spread":0.2118140880526007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}