{"id":"W7125907176","doi":"10.2196/83697","title":"Efficacy and Safety of HuaShiXiaoYin Decoction Combined With Secukinumab In Moderate To Severe Plaque Psoriasis: A Study Protocol For a Randomized Controlled Trial (Preprint)","year":2025,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Randomized controlled trial; Secukinumab; Decoction; Protocol (science); Randomization; Clinical trial","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007765384,0.004145505,0.006262993,0.001086446,0.001561194,0.001941438,0.001793982,0.003922386,0.02940555],"category_scores_gemma":[0.00556702,0.00177452,0.004258032,0.0009996179,0.003004193,0.001980064,0.001204468,0.005718994,0.005221792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001806362,"about_ca_system_score_gemma":0.003675709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001119305,"about_ca_topic_score_gemma":0.001650123,"domain_scores_codex":[0.9952177,0.002372049,0.0005137594,0.0006435876,0.0004698616,0.000783133],"domain_scores_gemma":[0.9977761,0.0005586399,0.0005211788,0.000362024,0.0002876771,0.0004942372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9864644,0.005030538,0.0001224408,0.0007036421,0.0004393181,0.00001406432,0.00003363087,0.0001731221,0.0009546729,0.0001792423,0.0006983418,0.00518657],"study_design_scores_gemma":[0.9771221,0.02094704,0.0003374908,0.00004747447,0.0002923854,0.000004626365,0.000008153612,0.0001335096,0.0002077676,0.0001260294,0.0007605085,0.00001295803],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.3573239,0.004900959,0.007814752,0.001724883,0.002630611,0.6078722,0.007171062,0.0008390224,0.009722537],"genre_scores_gemma":[0.280717,0.001874885,0.01124186,0.001659075,0.0009914064,0.6937181,0.002153225,0.0001020632,0.007542491],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02940555,"threshold_uncertainty_score":0.09837139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06734971314389039,"score_gpt":0.4474853152126152,"score_spread":0.3801356020687248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}