{"id":"W7126368175","doi":"10.1111/j.1399-5448-2008-00464","title":"The TrialNet Natural History Study of the Development of Type 1 Diabetes:objectives, design, and initial results","year":2009,"lang":"en","type":"article","venue":"Explore Bristol Research","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Natural history; Type 2 diabetes; Autoantibody; Diabetes mellitus; Cohort; Prospective cohort study; Natural history study; Type 1 diabetes; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001727845,0.00009188505,0.0001399327,0.0000438113,0.0002059227,0.00001311367,0.000330608,0.00006707809,0.000001396671],"category_scores_gemma":[0.001061442,0.00005789675,0.00003817169,0.0001802708,0.0002136525,0.000004219929,0.0001563147,0.0001977669,7.915359e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005541927,"about_ca_system_score_gemma":0.0003917242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001566145,"about_ca_topic_score_gemma":0.00005153328,"domain_scores_codex":[0.9982616,0.000559085,0.0002942963,0.0002239307,0.0003918895,0.0002691658],"domain_scores_gemma":[0.9990925,0.0001512113,0.0001167802,0.0002993338,0.0003012993,0.00003886577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01053205,0.003471123,0.006295849,0.00006856002,0.0009554242,0.000004639719,0.03064388,0.00009653427,0.518304,0.0001046839,0.1446853,0.2848379],"study_design_scores_gemma":[0.01909263,0.01853594,0.1926068,0.0002287819,0.00009990187,0.000001561208,0.03752681,0.0003337791,0.4689999,0.001050922,0.2604219,0.001101104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947299,0.003962001,0.000004964199,0.0001358084,0.0001624,0.000515762,0.00000308605,0.000003113968,0.000482989],"genre_scores_gemma":[0.9993173,0.0000935286,0.0000879853,0.00002058748,0.00004560994,0.0000190578,0.00001078244,0.000008877286,0.0003962822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2837368,"threshold_uncertainty_score":0.2360961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0804118247261695,"score_gpt":0.3460167163325478,"score_spread":0.2656048916063782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}