{"id":"W7128475515","doi":"10.3310/gjfg1715","title":"The clinical and cost-effectiveness of paravertebral blockade versus thoracic epidural blockade in reducing chronic post-thoracotomy pain: TOPIC2 RCT synopsis","year":2025,"lang":"en","type":"article","venue":"Health Technology Assessment","topic":"Anesthesia and Pain Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Health Technology Assessment Programme","keywords":"Randomized controlled trial; Blockade; Clinical trial; Health care; MEDLINE","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006560611,0.0002251503,0.000741322,0.0003685571,0.0002545748,0.0000135182,0.000227701,0.0003228213,0.000009177622],"category_scores_gemma":[0.0004206743,0.0001724881,0.00009958436,0.0006397451,0.0005064364,0.00003539485,0.0001448421,0.0008284054,0.000002164677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000501799,"about_ca_system_score_gemma":0.0009873837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001871031,"about_ca_topic_score_gemma":0.0001565017,"domain_scores_codex":[0.9963692,0.001478833,0.0008641773,0.0005022423,0.0002110937,0.000574433],"domain_scores_gemma":[0.9971373,0.001802313,0.0002469165,0.0006265356,0.00009147313,0.00009544386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009689126,0.0003429202,0.5944814,0.001646328,0.0002355635,0.00006738655,0.00004239665,0.00002332072,0.0001390628,0.01303777,0.0002835512,0.3887314],"study_design_scores_gemma":[0.004491001,0.003014847,0.9617113,0.001803168,0.0001482761,0.00002717396,0.001455397,0.003228268,0.0006051037,0.001037622,0.02226926,0.000208613],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9047414,0.004639239,0.001591828,0.08454875,0.0003047535,0.003631397,0.000001608934,0.0001477013,0.0003933183],"genre_scores_gemma":[0.9953284,0.001510291,0.001408484,0.001016588,0.00004475874,0.000470739,0.00001124517,0.00001585361,0.0001936988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3885228,"threshold_uncertainty_score":0.7033862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04357458146536971,"score_gpt":0.4521088659685185,"score_spread":0.4085342845031488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}