{"id":"W7131817338","doi":"10.5376/cge.2025.13.0007","title":"Genomic Insights into the Pathogenesis of Esophageal Adenocarcinoma","year":2025,"lang":"","type":"article","venue":"Cancer Genetics and Epigenetics","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Pathogenesis; Esophageal adenocarcinoma; Adenocarcinoma; Disease; Esophageal cancer; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002905431,0.0002631686,0.0003026152,0.000732952,0.0002213438,0.0006242587,0.0002952083,0.0005254365,0.002149639],"category_scores_gemma":[0.0004977417,0.0001817173,0.0003467524,0.000556386,0.0003959034,0.0003991659,0.0003408062,0.0004964988,0.0002541344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003471119,"about_ca_system_score_gemma":0.0003528273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009800125,"about_ca_topic_score_gemma":0.001377007,"domain_scores_codex":[0.9998477,0.00003497101,0.00001045906,0.00003986057,0.00004112799,0.00002586381],"domain_scores_gemma":[0.9998477,0.00005291758,0.00004616099,0.00001806267,0.00002018604,0.00001507594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001621002,0.000204761,0.2193218,0.001220351,0.0009395647,0.01445838,0.001250787,0.006112905,0.4001745,0.05633045,0.007373491,0.2909921],"study_design_scores_gemma":[0.0001890443,0.0006500139,0.6523696,0.0006950184,0.001239218,0.02519078,0.001920142,0.006568105,0.09552655,0.0627507,0.1527886,0.000112327],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.7942938,0.1397243,0.01857886,0.01856591,0.0006199685,0.00005303503,0.002641418,0.0003349986,0.0251877],"genre_scores_gemma":[0.967074,0.02614749,0.002446835,0.0009956509,0.0002630404,0.00001113545,0.0005450454,0.00002201195,0.0024948],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002149639,"threshold_uncertainty_score":0.007191241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01779531221615521,"score_gpt":0.3041853820242475,"score_spread":0.2863900698080923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}