{"id":"W7131818921","doi":"10.5376/ijmms.2024.14.0030","title":"Mapping the Tumor Microenvironment in Colon Cancer with Spatial Transcriptomics","year":2024,"lang":"","type":"article","venue":"International Journal of Molecular Medical Science","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Tumor microenvironment; Colorectal cancer; Transcriptome; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001339157,0.0001469414,0.0002174901,0.0004190147,0.0002246022,0.0004991005,0.000181411,0.0002775206,0.0005965682],"category_scores_gemma":[0.0001556128,0.0001480769,0.0001936126,0.0005006729,0.0002937173,0.0003424493,0.0002171153,0.0003924058,0.0001875973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002995035,"about_ca_system_score_gemma":0.0003239324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002601456,"about_ca_topic_score_gemma":0.005406738,"domain_scores_codex":[0.9999079,0.0000125848,0.000003561364,0.00002673363,0.0000288483,0.00002042267],"domain_scores_gemma":[0.9999352,0.00002032142,0.00001498436,0.000009047838,0.00001373988,0.000006783501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006893933,0.000006991877,0.002394193,0.00006875327,0.000009912114,0.00006786004,0.00004157624,0.00115096,0.9900954,0.0003736758,0.0001227543,0.005599023],"study_design_scores_gemma":[0.00001805365,0.000129041,0.09511983,0.00002537905,0.00007607709,0.0007713276,0.0007011083,0.03159672,0.8620928,0.001938087,0.007494328,0.00003718565],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9182084,0.005617966,0.06982157,0.0005249142,0.00004785047,0.00004803313,0.002491493,0.0004417819,0.002797937],"genre_scores_gemma":[0.9719236,0.002558365,0.02321941,0.0001275772,0.00002525457,0.00006046498,0.0007610254,0.00004796709,0.001276192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002601456,"threshold_uncertainty_score":0.00517261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01157031339473105,"score_gpt":0.2616822411198308,"score_spread":0.2501119277250998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}