{"id":"W7131841150","doi":"10.5376/cge.202412.0024","title":"Modulating the Immune Microenvironment for Colon Cancer Therapy","year":2024,"lang":"","type":"article","venue":"Cancer Genetics and Epigenetics","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Colorectal cancer; Immune system; Tumor microenvironment; Immunotherapy; Cancer; Cancer therapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005490644,0.0006717453,0.0006218015,0.000117355,0.001156517,0.0002944792,0.0005351948,0.0005697325,0.0010021],"category_scores_gemma":[0.00001844701,0.0005079502,0.0003608255,0.0002282694,0.00103914,0.00005047352,0.0002137609,0.0005728186,0.00002776945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000179375,"about_ca_system_score_gemma":0.0004506824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003308254,"about_ca_topic_score_gemma":0.0000586539,"domain_scores_codex":[0.9968281,0.0003192013,0.0008783537,0.0008421915,0.0001016124,0.001030587],"domain_scores_gemma":[0.9983682,0.0005560713,0.0002248239,0.0006872494,0.0001042992,0.00005932303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007625442,0.00008899366,0.0005863305,0.000232582,0.001672254,0.000002449591,0.003025814,0.001094395,0.5298609,0.0002439237,0.001326688,0.4611031],"study_design_scores_gemma":[0.001354642,0.0007500816,0.006984148,0.0004040257,0.0003276536,0.00001770385,0.0003225717,0.002216202,0.3391713,0.0003156309,0.6475975,0.0005386127],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3913389,0.5994836,0.0008184511,0.002690333,0.004084548,0.001105667,0.0004222904,0.00002695597,0.00002922771],"genre_scores_gemma":[0.4658231,0.5262118,0.000108344,0.0003835796,0.0003246958,0.0004918125,0.00002421546,0.00009440121,0.006538054],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6462708,"threshold_uncertainty_score":0.9999111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02509700434380976,"score_gpt":0.2916437167457404,"score_spread":0.2665467124019306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}