{"id":"W7131844708","doi":"10.5376/jvr.2024.14.0011","title":"The Evolution of mRNA Vaccine Technology: A Comprehensive Review","year":2024,"lang":"","type":"article","venue":"Journal of Vaccine Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Messenger RNA; Immune system; DNA vaccination; Disease; Vaccination","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002192779,0.001000024,0.001761502,0.00221887,0.0003804125,0.001781349,0.00132331,0.001887474,0.001498475],"category_scores_gemma":[0.002033191,0.0005675475,0.0005797012,0.001951548,0.001188731,0.003065787,0.001048383,0.002658387,0.0009938726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001391956,"about_ca_system_score_gemma":0.001560836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008116618,"about_ca_topic_score_gemma":0.001195796,"domain_scores_codex":[0.9995542,0.00008120909,0.00005995651,0.00009314664,0.0001553307,0.00005607214],"domain_scores_gemma":[0.9986441,0.0009405184,0.00009947031,0.00003483341,0.0002169163,0.00006422665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001953823,0.0001488617,0.0004276785,0.01851643,0.0001069882,0.000307688,0.0001739998,0.001255624,0.01993025,0.01236294,0.02053423,0.9260399],"study_design_scores_gemma":[0.00002447639,0.0002187144,0.0005987723,0.002834996,0.0001552664,0.0008968453,0.0001071302,0.0003313072,0.009661128,0.004385914,0.9807352,0.00005015634],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003174499,0.9975421,0.0007800673,0.000502056,0.0002459741,0.000005397548,0.00001364495,0.000008719068,0.000584698],"genre_scores_gemma":[0.001469732,0.9962351,0.001101871,0.0004641449,0.0002737945,0.000009599542,0.00003338284,0.000006325492,0.0004059571],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00221887,"threshold_uncertainty_score":0.01159668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03592533612490954,"score_gpt":0.3885145220710462,"score_spread":0.3525891859461366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}