{"id":"W7131851270","doi":"10.3389/fimmu.2024.1513595/full","title":"Loss of Parp7 increases type I interferon signalling and reduces pancreatic tumour growth by enhancing immune cell infiltration","year":2024,"lang":"en","type":"other","venue":"Lithuanian University of Health Sciences","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Glycomics Network; Canadian Institutes of Health Research; Norges Forskningsråd; Associazione Italiana per la Ricerca sul Cancro","keywords":"Interferon; Immune system; Signalling; Cell growth; Infiltration (HVAC); Cell; Cytokine; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002173705,0.0003751497,0.0004364997,0.0005371489,0.0002276484,0.0007617369,0.00046472,0.0007513432,0.02031292],"category_scores_gemma":[0.000170282,0.0002092509,0.0004058727,0.0002300772,0.0004615509,0.0003891384,0.0003400814,0.001288184,0.006382237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003262385,"about_ca_system_score_gemma":0.0003221584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003304207,"about_ca_topic_score_gemma":0.0003559373,"domain_scores_codex":[0.9996848,0.00005858008,0.00002429901,0.0000527881,0.00008719196,0.00009227997],"domain_scores_gemma":[0.9998173,0.0000217432,0.00004908122,0.00002444656,0.0000170487,0.00007037491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004962584,0.0007297993,0.00165503,0.0006146289,0.0001281607,0.0005183434,0.00006170983,0.0006907374,0.9434913,0.001836328,0.008382513,0.03692887],"study_design_scores_gemma":[0.0005667584,0.004610331,0.01279964,0.00008347897,0.0001534829,0.001389465,0.0002927534,0.002157647,0.9193115,0.0006523782,0.05794632,0.00003613255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9253049,0.01158403,0.005990237,0.002462229,0.0009919741,0.0001791997,0.00596014,0.001514596,0.0460127],"genre_scores_gemma":[0.9444637,0.00281215,0.002136047,0.0005464992,0.00009098014,0.0001587789,0.006220194,0.00024286,0.04332878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02031292,"threshold_uncertainty_score":0.06795353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01381316900583059,"score_gpt":0.2418132280902316,"score_spread":0.228000059084401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}