{"id":"W7131881870","doi":"10.5376/jvr.2024.14.0030","title":"mRNA Technology in Vaccine Development: Current Status and Future Prospects","year":2024,"lang":"","type":"article","venue":"Journal of Vaccine Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Current (fluid); Messenger RNA; DNA vaccination; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00771868,0.0006575408,0.001563561,0.001087639,0.000494703,0.002852081,0.001245319,0.002286281,0.00621382],"category_scores_gemma":[0.00317463,0.0003605765,0.0005854024,0.001324588,0.002594179,0.004019896,0.0008086443,0.001727757,0.002357139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001021639,"about_ca_system_score_gemma":0.002466647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008354249,"about_ca_topic_score_gemma":0.001298121,"domain_scores_codex":[0.9988869,0.0004377265,0.0000992129,0.0001628891,0.0002387732,0.0001745988],"domain_scores_gemma":[0.9964975,0.002395427,0.0002684176,0.00009421519,0.0005077822,0.0002366515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001389878,0.000690427,0.003114529,0.006015778,0.00007553938,0.0003779449,0.0002894439,0.001664319,0.03616285,0.02097503,0.01144219,0.917802],"study_design_scores_gemma":[0.0004091052,0.007030044,0.006404918,0.005837548,0.0006412487,0.002938876,0.001998166,0.006427467,0.05121369,0.05050508,0.8663835,0.000210287],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006683014,0.9689775,0.01005907,0.008656389,0.0006921829,0.00004069197,0.00005439551,0.00008292181,0.004753773],"genre_scores_gemma":[0.05004392,0.9317746,0.01174552,0.001889716,0.001803637,0.00009452642,0.000167483,0.00002771291,0.002452995],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00771868,"threshold_uncertainty_score":0.04082078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02489019145154764,"score_gpt":0.3648543258926246,"score_spread":0.3399641344410769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}