{"id":"W7131881870","doi":"10.5376/jvr.2024.14.0030","title":"mRNA Technology in Vaccine Development: Current Status and Future Prospects","year":2024,"lang":"","type":"article","venue":"Journal of Vaccine Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Current (fluid); Messenger RNA; DNA vaccination; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001966664,0.0003174501,0.0005069747,0.001955923,0.0001332973,0.0002133274,0.0005029825,0.0004291541,0.0001143583],"category_scores_gemma":[0.000211905,0.0002577555,0.0001196134,0.001380673,0.00005544471,0.00003636754,0.0005622465,0.002130172,0.00002987679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002233443,"about_ca_system_score_gemma":0.001883902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007560103,"about_ca_topic_score_gemma":0.00007468653,"domain_scores_codex":[0.9965897,0.0002030464,0.001067359,0.0005628885,0.0005979908,0.0009790437],"domain_scores_gemma":[0.9981343,0.00005332382,0.0001803575,0.0003284435,0.000993768,0.0003098169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001406712,0.0005772893,0.04770914,0.001120181,0.0005028406,0.0007668945,0.0008607045,0.000008719401,0.1490249,0.0004367469,0.01324194,0.7843439],"study_design_scores_gemma":[0.002572412,0.003495498,0.02192275,0.001911708,0.00004677999,0.0007531881,0.001401517,0.0001298694,0.1337089,0.001159044,0.8324447,0.0004536755],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6655694,0.3285988,0.00002402917,0.004663468,0.0007815995,0.0002207089,0.000005286738,0.000004061377,0.0001325892],"genre_scores_gemma":[0.8106477,0.1869635,0.0001871826,0.00001524906,0.001837256,0.000009702776,0.000008002418,0.00003265449,0.0002987525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8192027,"threshold_uncertainty_score":0.9999875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02489019145154764,"score_gpt":0.3648543258926246,"score_spread":0.3399641344410769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}