{"id":"W7132359792","doi":"","title":"A defined O-antigen polysaccharide mutant of Francisella tularensis live vaccine strain has attenuated virulence while retaining its protective capacity","year":2007,"lang":"en","type":"article","venue":"NPARC","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Francisella tularensis; Virulence; Attenuated vaccine; Pathogen; Tularemia; Immune system; Mutant; Immunity; Streptococcus suis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009386156,0.0002811656,0.0001868143,0.0001198072,0.00009226835,0.0001343366,0.0002150972,0.0002406277,0.000553536],"category_scores_gemma":[0.0001754296,0.00008070208,0.0001719141,0.00009445126,0.0002024844,0.0001188915,0.0001367176,0.0003030572,0.0002128009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002051136,"about_ca_system_score_gemma":0.0001979731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001031619,"about_ca_topic_score_gemma":0.001114568,"domain_scores_codex":[0.9999185,0.00001223524,0.00001021997,0.00001394461,0.00002475798,0.00002027901],"domain_scores_gemma":[0.9998834,0.00002522893,0.00003709007,0.00001549786,0.00001420811,0.00002457649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004385342,0.00003677368,0.0001250694,0.00001044894,0.000002472685,0.00003070875,0.000007313498,0.00004955212,0.9991437,0.00007992447,0.00001095037,0.0004592524],"study_design_scores_gemma":[0.00002561585,0.0009899139,0.003935196,0.000008387776,0.00001859306,0.0005571592,0.00003364986,0.002075882,0.9910897,0.00005093257,0.001207225,0.000007791992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981778,0.0001159429,0.001287669,0.00002878109,0.000008233661,0.000009726173,0.00008398254,0.00002323661,0.0002647808],"genre_scores_gemma":[0.9963157,0.000106373,0.001950777,0.00001800226,0.000004943649,0.00001659315,0.0005897743,0.00001677829,0.0009812176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031619,"threshold_uncertainty_score":0.002051294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03517160132549611,"score_gpt":0.2567450487767475,"score_spread":0.2215734474512514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}