{"id":"W7132868767","doi":"","title":"NoncanonicalTransmission of Biological Information and Master-regulation of Signaling by the Zinc Finger Proteins MSTR-1 and MSTR-2","year":2022,"lang":"","type":"dissertation","venue":"TSpace","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Amgen (Canada)","funders":"","keywords":"Germline; Zinc finger; Transcription factor; Germ cell; Epigenetics; Piwi-interacting RNA; Signal transduction; Transcription (linguistics); Gene silencing; Regulation of gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000155444,0.0004401856,0.0001569099,0.0001744372,0.0001871428,0.000393464,0.0002588814,0.0002640756,0.001622099],"category_scores_gemma":[0.0001257336,0.0001630797,0.0003490532,0.00009573937,0.0003447692,0.0003324689,0.0005241453,0.0005456905,0.0005897785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003813937,"about_ca_system_score_gemma":0.0002083119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002500809,"about_ca_topic_score_gemma":0.0004945933,"domain_scores_codex":[0.9998257,0.000009895629,0.000009880353,0.0000570673,0.00005501083,0.00004245106],"domain_scores_gemma":[0.9998729,0.00001090397,0.00005422368,0.00002093468,0.00001342742,0.00002747938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005382238,0.000006676107,0.0008528991,0.00002703305,0.000003184487,0.0001015747,0.00002160449,0.00007040425,0.9959908,0.0008115429,0.0000699904,0.001990458],"study_design_scores_gemma":[0.0000136633,0.000106806,0.01260601,0.000008613571,0.00001016806,0.0009103336,0.00004590998,0.001571856,0.9773072,0.0004017088,0.007008779,0.000009072599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9780639,0.002966318,0.01301871,0.0003399389,0.00007687651,0.00001875103,0.0004708283,0.0003792687,0.00466542],"genre_scores_gemma":[0.9899295,0.001000844,0.00341257,0.00006712661,0.00002160464,0.00001673749,0.0003584211,0.00003851223,0.005154774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001622099,"threshold_uncertainty_score":0.005426526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01448222695706017,"score_gpt":0.2676708608231738,"score_spread":0.2531886338661136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}