{"id":"W7132874529","doi":"","title":"The Complicity of GABAergic Neurotransmission in Ictogenesis during Acute Hyperexcitabilty","year":2021,"lang":"","type":"dissertation","venue":"TSpace","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Epilepsy Research Program of the Ontario Brain Institute","keywords":"GABAergic; GABAA receptor; Neurotransmission; Optogenetics; GABA transporter; Inhibitory postsynaptic potential; Excitatory postsynaptic potential; gamma-Aminobutyric acid; Electrophysiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001178501,0.0002096947,0.0001870285,0.0001799647,0.0001163245,0.0002352724,0.0001730691,0.0001839139,0.0004858253],"category_scores_gemma":[0.0001320252,0.00009762469,0.000205919,0.00009205067,0.0003328622,0.0002814904,0.0003351874,0.0005466354,0.00009160731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002808925,"about_ca_system_score_gemma":0.0001969496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005985746,"about_ca_topic_score_gemma":0.0009473374,"domain_scores_codex":[0.9999269,0.000008370694,0.000009523254,0.00000937738,0.00001847884,0.00002735656],"domain_scores_gemma":[0.9998958,0.00001656275,0.0000385421,0.00001543679,0.00001394751,0.00001979137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002482031,0.0000134479,0.001269626,0.00005243645,0.000008384936,0.0004372833,0.00005273177,0.0001820061,0.9955618,0.0002865109,0.00002300251,0.001864587],"study_design_scores_gemma":[0.00003279054,0.0006699975,0.07254548,0.0000249581,0.00005931059,0.001421307,0.000292388,0.001345936,0.920592,0.0009592177,0.002042335,0.00001428902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949699,0.001211077,0.002389075,0.00007133808,0.00001689755,0.00001671343,0.00006223666,0.00003958214,0.001223187],"genre_scores_gemma":[0.998741,0.0004639848,0.0002971552,0.00002801405,0.000003624895,0.00001351313,0.00004632853,0.000003381388,0.000403122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005985746,"threshold_uncertainty_score":0.002038002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05789869638258678,"score_gpt":0.4101826584128644,"score_spread":0.3522839620302776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}