{"id":"W7132883653","doi":"","title":"Structural and functional studies of the Polo like kinase Sak/Plk4","year":2007,"lang":"","type":"dissertation","venue":"TSpace","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; National Cancer Institute; Medical Research Council; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Polo-like kinase; PLK1; Centrosome; Mitosis; Protein kinase domain; Kinase; Centriole; Subcellular localization","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001509276,0.0004575758,0.000166509,0.0001117528,0.0003348766,0.0001981432,0.0005719411,0.0002633365,0.001684148],"category_scores_gemma":[0.0002027835,0.0001676117,0.0003243242,0.0001364879,0.0002819354,0.0002899742,0.0001973741,0.0008345116,0.0003679853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007397619,"about_ca_system_score_gemma":0.0003179174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002366708,"about_ca_topic_score_gemma":0.001223992,"domain_scores_codex":[0.9999385,0.00001075674,0.000003517444,0.00001126542,0.00001808755,0.00001776957],"domain_scores_gemma":[0.9999197,0.00001279371,0.00002071894,0.000003914395,0.0000135688,0.00002925235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006185444,0.0001478963,0.001624433,0.0002330019,0.00003207949,0.0003520594,0.00008142807,0.004735454,0.9867921,0.001320273,0.0003509569,0.003711789],"study_design_scores_gemma":[0.0002002194,0.0006318068,0.01889421,0.00004334134,0.0001003106,0.0009786026,0.0003288861,0.02829196,0.9310136,0.0009424989,0.01853429,0.00004025082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945616,0.001744971,0.001253077,0.0003367659,0.0000407506,0.00001313331,0.0002653332,0.00002137074,0.001763043],"genre_scores_gemma":[0.9928654,0.001507511,0.00181346,0.00008707991,0.00002184453,0.00001319604,0.001380284,0.0000161696,0.002294835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002366708,"threshold_uncertainty_score":0.005634069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01808171008419737,"score_gpt":0.3296223652924702,"score_spread":0.3115406552082728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}