{"id":"W7132907472","doi":"","title":"An integrated methodological approach for the study of the transplacental transfer of glyburide: From the subcellular to the clinical perspective","year":2008,"lang":"","type":"dissertation","venue":"TSpace","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Transplacental; Placenta; Efflux; Abcg2; Fetus; Human placenta; Syncytiotrophoblast; Fetal membrane","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004027721,0.0008897302,0.001282669,0.001637276,0.000542991,0.002096769,0.001677854,0.001513853,0.002592303],"category_scores_gemma":[0.003014527,0.0005522622,0.0009051221,0.001445924,0.001532655,0.001679809,0.002314268,0.002912102,0.001371732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007913581,"about_ca_system_score_gemma":0.001646023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006719208,"about_ca_topic_score_gemma":0.0007810181,"domain_scores_codex":[0.998226,0.0008343405,0.0001251118,0.0003625209,0.0003566543,0.00009544023],"domain_scores_gemma":[0.9987645,0.0003806441,0.000149405,0.0003454052,0.0002854218,0.00007464749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003923984,0.0002128901,0.002561144,0.001527198,0.0002030578,0.0005877613,0.0005435587,0.001445208,0.8884268,0.02971151,0.0008030795,0.07358538],"study_design_scores_gemma":[0.0001643363,0.003889753,0.02215336,0.0006989447,0.0009978005,0.008779678,0.002232363,0.04460127,0.6728283,0.07504153,0.1682854,0.000327255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.02914854,0.0113802,0.9522024,0.00115553,0.0003571891,0.0005207452,0.0003539534,0.0003649137,0.004516632],"genre_scores_gemma":[0.1341493,0.01760512,0.8396078,0.0007114894,0.0002664944,0.002528413,0.0005694786,0.0003629827,0.004198865],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004027721,"threshold_uncertainty_score":0.02130091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1521217556301506,"score_gpt":0.4380132260010738,"score_spread":0.2858914703709232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}