{"id":"W7132917525","doi":"","title":"Regulation of p27(KIP1) by the PI3K/PKB pathway and its role in cell cycle progression in human cancer","year":2004,"lang":"","type":"dissertation","venue":"TSpace","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bibliographical Society of Canada","funders":"National Cancer Institute; U.S. Department of Defense","keywords":"Cyclin D; Cyclin-dependent kinase; Cyclin A; Cyclin A2; Protein kinase B; Cell cycle; Cyclin D1; Cyclin; Cyclin-dependent kinase complex; Cyclin E","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008269517,0.0002032827,0.0001012106,0.000247087,0.000189363,0.0002822301,0.00009010657,0.0001272917,0.0007697014],"category_scores_gemma":[0.00007073924,0.0001040731,0.00009985849,0.0001953077,0.0001832981,0.000119266,0.0001408421,0.0003218192,0.0002899374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004037478,"about_ca_system_score_gemma":0.0003499296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001267747,"about_ca_topic_score_gemma":0.001051705,"domain_scores_codex":[0.9999676,0.000006424002,0.000002170512,0.000006230574,0.000008998179,0.000008630288],"domain_scores_gemma":[0.9999808,0.00000263548,0.000006402277,0.000001927283,0.000003244894,0.000004975724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004358443,0.00005276627,0.001651601,0.0002616369,0.00001037101,0.0003552552,0.00007078585,0.0003476873,0.9747464,0.000963024,0.0002845578,0.02082006],"study_design_scores_gemma":[0.00004273217,0.000301219,0.03047296,0.00003144557,0.00002742402,0.001804813,0.00008837381,0.00132456,0.9430988,0.0009887647,0.02181023,0.000008705802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9384016,0.05289633,0.003546457,0.0005937122,0.00003895786,0.00003819211,0.0003846998,0.000109179,0.003990782],"genre_scores_gemma":[0.9728766,0.02224424,0.001368192,0.00005151831,0.00001422262,0.00003414069,0.0003500129,0.0000114101,0.003049685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001267747,"threshold_uncertainty_score":0.002929389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00875311004613932,"score_gpt":0.3183113218817993,"score_spread":0.30955821183566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}