{"id":"W7132920470","doi":"","title":"Detection of Cystic Fibrosis Transmembrane Conductance Regulator ∆F508 Gene Mutation Using a Paper-Based Nucleic Acid Hybridization Assay and a Smartphone Camera","year":2018,"lang":"","type":"dissertation","venue":"TSpace","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Oligonucleotide; Fluorophore; Mutant; In situ hybridization; Nucleic acid thermodynamics; Nucleic acid; Mutation; Cystic fibrosis transmembrane conductance regulator","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003829218,0.0007316258,0.0009058228,0.0004724967,0.000340147,0.0001241258,0.0001217559,0.0007761453,0.0002751305],"category_scores_gemma":[0.000242543,0.0008462043,0.000259324,0.001082849,0.0002070869,0.0003702551,0.00001089422,0.0004479174,0.00001714382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003055389,"about_ca_system_score_gemma":0.0001250011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004999535,"about_ca_topic_score_gemma":0.0003283625,"domain_scores_codex":[0.9969084,0.000222832,0.0009825598,0.000837096,0.0005377842,0.0005113566],"domain_scores_gemma":[0.9980634,0.0001706036,0.0005989043,0.0004303669,0.0005105961,0.0002261102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005134454,0.00006788437,0.000009281826,0.00224692,0.0001645845,0.000006089799,0.00146154,0.01290497,0.9763043,0.00001472728,0.00000397425,0.006302321],"study_design_scores_gemma":[0.0008493407,0.0002803414,0.0009554299,0.0006493392,0.0005474008,0.00002501701,0.0003862012,0.4320311,0.563695,0.00006346999,0.00003012974,0.0004873094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8675422,0.001519757,0.1292326,0.00006559124,0.000791037,0.0006075533,0.00005883993,0.0001233377,0.00005909761],"genre_scores_gemma":[0.9909011,0.0002053005,0.007847311,0.00002067359,0.0002945299,0.00002580135,0.0002958742,0.000183822,0.0002256569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4191261,"threshold_uncertainty_score":0.9993989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01106087201336885,"score_gpt":0.249188834222098,"score_spread":0.2381279622087291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}