{"id":"W7132926896","doi":"","title":"Clonal Hematopoiesis of Indeterminate Potential as a Mediator of Radiation Toxicities","year":2024,"lang":"","type":"dissertation","venue":"TSpace","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Haematopoiesis; Mediator; Cancer; Radiation therapy; Stem cell; Fibrosis; Carcinogenesis; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007438468,0.0007228918,0.001698037,0.001197679,0.00008480967,0.00004197818,0.0003437555,0.001088928,0.002028761],"category_scores_gemma":[0.001268611,0.0007506621,0.0007029448,0.0007398346,0.000274888,0.0002122399,0.00006538181,0.0008050313,0.0002536457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002252834,"about_ca_system_score_gemma":0.001529648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003797418,"about_ca_topic_score_gemma":0.00004057117,"domain_scores_codex":[0.9952035,0.0002592246,0.001557329,0.0007115865,0.00176517,0.0005031725],"domain_scores_gemma":[0.9960527,0.0005785073,0.0017509,0.0006580187,0.0006621382,0.0002977151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006570807,0.001548091,0.003155,0.0803608,0.00575773,0.0007727583,0.2614554,0.0004752771,0.576741,0.007641264,0.01290773,0.04261407],"study_design_scores_gemma":[0.002983827,0.00253367,0.00983107,0.004702733,0.003569264,0.0001061469,0.03840953,0.002494756,0.9329147,0.0008599076,0.0007881087,0.000806255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738976,0.01648141,0.00005448991,0.0007289459,0.003570988,0.001281219,0.0001192745,0.0000771049,0.003789007],"genre_scores_gemma":[0.9800882,0.001600807,0.0002551847,0.00006517421,0.0008750809,0.00008338994,0.00102275,0.000159582,0.01584983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3561737,"threshold_uncertainty_score":0.9994944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006051942502847026,"score_gpt":0.329365452175201,"score_spread":0.3233135096723539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}