{"id":"W7132936636","doi":"","title":"The role of local structure propensity and nonnative interactions in protein folding","year":2008,"lang":"","type":"dissertation","venue":"TSpace","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Folding (DSP implementation); Protein folding; Helix (gastropod); Protein structure; Native state; Kinetics; Energetics; Lattice protein","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006433685,0.0002847733,0.0003657563,0.0002636847,0.0004184276,0.0009819663,0.0002514954,0.0003416378,0.0008182609],"category_scores_gemma":[0.0007512362,0.0001835397,0.0003423713,0.0001775407,0.0006360206,0.0008464419,0.0006575565,0.0005302737,0.0001777704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000278822,"about_ca_system_score_gemma":0.0002706726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001281599,"about_ca_topic_score_gemma":0.0001943589,"domain_scores_codex":[0.9997134,0.00007783829,0.00001971323,0.00007955471,0.00006940162,0.0000402148],"domain_scores_gemma":[0.9993138,0.0003366745,0.0001817628,0.00006252543,0.00004103303,0.00006426359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0003681934,0.0001653641,0.03940841,0.0005024253,0.0001256012,0.0007541805,0.0006629226,0.02056885,0.8562497,0.02655167,0.0001583218,0.05448426],"study_design_scores_gemma":[0.00002771213,0.001679868,0.1317802,0.0001224479,0.0001792992,0.002663478,0.001419988,0.1038113,0.6799195,0.07082493,0.007392812,0.0001784699],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846175,0.002401346,0.01110798,0.0001478195,0.00001299645,0.00001028729,0.00001506708,0.00002599335,0.001660926],"genre_scores_gemma":[0.9960914,0.001153173,0.002317958,0.00002076839,0.00000986325,0.000008743948,0.00001512445,0.0000108645,0.0003719896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009819663,"threshold_uncertainty_score":0.003402531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006719808905062216,"score_gpt":0.2820797579779989,"score_spread":0.2753599490729366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}