{"id":"W7132937437","doi":"","title":"Genetically Engineering Microbes for Detecting and Treating Inflammatory Bowel Disease","year":2023,"lang":"","type":"dissertation","venue":"TSpace","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Inflammatory bowel disease; Disease; Genetically engineered; Inflammation; Gastrointestinal tract; Therapeutic approach; Inflammatory Bowel Diseases","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005967515,0.0004063801,0.0003440513,0.0004730005,0.0002279461,0.000839662,0.0003970819,0.0008125597,0.0009983706],"category_scores_gemma":[0.0006456609,0.0002199399,0.0004757262,0.0003473478,0.0003702777,0.000574594,0.0005029689,0.001357621,0.0005303295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004560172,"about_ca_system_score_gemma":0.0003973506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004505103,"about_ca_topic_score_gemma":0.0005590594,"domain_scores_codex":[0.9994404,0.0001165875,0.00003885455,0.00009450271,0.0002489461,0.00006079314],"domain_scores_gemma":[0.9997267,0.00005746539,0.00008015756,0.00003093844,0.0000601041,0.00004455619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006354209,0.00006646255,0.0002651713,0.0003336379,0.0000190245,0.0001401939,0.00005936091,0.0007970739,0.9750312,0.003003258,0.00068493,0.01953604],"study_design_scores_gemma":[0.00003154951,0.000781506,0.001406741,0.0001511891,0.00008739814,0.0007833792,0.00008191166,0.003581437,0.9078858,0.0009875232,0.08417986,0.00004159181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5280861,0.06984652,0.3565014,0.005676329,0.00339129,0.0009458571,0.002448769,0.002606373,0.03049747],"genre_scores_gemma":[0.7417526,0.0405378,0.2013237,0.001127205,0.0001732283,0.000461079,0.001640566,0.000319378,0.01266449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009983706,"threshold_uncertainty_score":0.003339887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008104535999594781,"score_gpt":0.2902670029459403,"score_spread":0.2821624669463456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}