{"id":"W7132958527","doi":"","title":"Chemical genomics in yeast: linking biologically active compounds to their intracellular targets","year":2006,"lang":"","type":"dissertation","venue":"TSpace","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Saccharomyces cerevisiae; Mutant; Mode of action; Mechanism of action; Yeast; Functional genomics; Gene; Mutation; Genomics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002225831,0.0005428624,0.000618253,0.0008160123,0.0002388637,0.0006854754,0.0002475107,0.0003256922,0.0008797101],"category_scores_gemma":[0.0005969341,0.0002191658,0.0007831918,0.001579593,0.0002679121,0.0002887859,0.0004138142,0.0006886182,0.0002967267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004892192,"about_ca_system_score_gemma":0.0004890465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003594321,"about_ca_topic_score_gemma":0.003159842,"domain_scores_codex":[0.9997646,0.00003748673,0.00001339324,0.00009088619,0.00006985087,0.00002381489],"domain_scores_gemma":[0.9997531,0.00009497887,0.00007112355,0.00003038038,0.00002644921,0.00002395762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008220681,0.0001806144,0.03938049,0.001179258,0.0003096014,0.0004464868,0.0001433716,0.02749726,0.8520644,0.002887331,0.001472373,0.07361674],"study_design_scores_gemma":[0.0001510823,0.001766186,0.2794844,0.0001319511,0.0008234876,0.001162974,0.0006673645,0.1027107,0.5478705,0.01825051,0.046845,0.0001359375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9061921,0.005788751,0.06757807,0.0007418127,0.00005314658,0.0001641741,0.01372616,0.001734458,0.004021245],"genre_scores_gemma":[0.9059942,0.00587716,0.07289244,0.0004800691,0.00003095215,0.0001852977,0.01331777,0.0001565195,0.001065404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003594321,"threshold_uncertainty_score":0.007146776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00901417641192067,"score_gpt":0.2569106030905152,"score_spread":0.2478964266785945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}