{"id":"W7132976823","doi":"","title":"Anionic Acyl Methyl Phosphates for the Synthesis of Hemoglobin-Based Oxygen Therapeutics","year":2024,"lang":"","type":"dissertation","venue":"TSpace","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Cooperativity; Reagent; Oxygen; Hemoglobin; Blood substitute; Intramolecular force; Molecule","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005065564,0.0006706729,0.0006119586,0.0000970861,0.0002791251,0.00009636023,0.0005773451,0.00100057,0.0001479292],"category_scores_gemma":[0.0002356771,0.0004939748,0.0007988801,0.0003424988,0.000177646,0.000004519597,0.0000606621,0.0003336194,0.00002081559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006287793,"about_ca_system_score_gemma":0.0007357857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001129915,"about_ca_topic_score_gemma":0.00007992808,"domain_scores_codex":[0.9975657,0.0001161989,0.0006170485,0.0008497757,0.00033745,0.0005138429],"domain_scores_gemma":[0.9974918,0.000506076,0.0004817976,0.0009446023,0.0004841981,0.00009147709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001773645,0.0001151926,0.00004544149,0.001749688,0.002277892,0.000001810225,0.001429452,0.000516257,0.9258816,0.0002779316,0.003236344,0.06269471],"study_design_scores_gemma":[0.0004455131,0.0004421344,0.000169233,0.0002083977,0.002079018,0.00000369164,0.003836886,0.002200923,0.8616201,0.0001974852,0.1283175,0.0004790114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7086908,0.2391728,0.0214368,0.006199368,0.01202434,0.006433688,0.0008821235,0.0001300874,0.005030106],"genre_scores_gemma":[0.9859516,0.003730889,0.000936644,0.0004769027,0.0006534647,0.000352934,0.001068104,0.0001562916,0.006673153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2772609,"threshold_uncertainty_score":0.9997512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01618863872124432,"score_gpt":0.3181968791151159,"score_spread":0.3020082403938716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}