{"id":"W7133034254","doi":"","title":"Leveraging CRISPR-Cas to Examine the Interplay Between Legionella pneumophila and Mobile Genetic Elements","year":2022,"lang":"","type":"dissertation","venue":"TSpace","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Connaught Fund; University of Toronto","keywords":"Legionella pneumophila; Mobile genetic elements; Lytic cycle; Axenic; Legionella; Genome; Bacteria; CRISPR","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006691744,0.000481205,0.0005792014,0.0006676551,0.0003821004,0.001345655,0.0005086268,0.0008412059,0.001986804],"category_scores_gemma":[0.001313901,0.0004062283,0.0007197559,0.0004214401,0.000374443,0.0006798073,0.0008729538,0.001504747,0.001152625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000518259,"about_ca_system_score_gemma":0.0005759941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001212542,"about_ca_topic_score_gemma":0.00211803,"domain_scores_codex":[0.9992797,0.00006205116,0.00006360711,0.000223581,0.0002896985,0.00008140091],"domain_scores_gemma":[0.9994401,0.0002089406,0.00009990092,0.00007229573,0.00007460473,0.0001041664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002000091,0.00008744302,0.006766926,0.0005846736,0.00009440572,0.0004437983,0.0002813426,0.003013858,0.947747,0.002142899,0.002590447,0.03604724],"study_design_scores_gemma":[0.00004528148,0.0005822994,0.01897432,0.0001692588,0.0001424763,0.00114663,0.0004104456,0.03944609,0.8692864,0.003208607,0.06640556,0.0001827048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7657397,0.007757463,0.1808506,0.002573702,0.0008096423,0.0005525663,0.01016237,0.009808087,0.02174585],"genre_scores_gemma":[0.7732376,0.004473611,0.2023934,0.002160794,0.00009592364,0.0003978394,0.006370889,0.0008259666,0.01004391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001986804,"threshold_uncertainty_score":0.006646514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02009593105281936,"score_gpt":0.3710080004082462,"score_spread":0.3509120693554268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}