{"id":"W7133041215","doi":"","title":"Scalable bioprocess for controlled differentiation of embryonic stem cells to hematopoietic progenitors","year":2004,"lang":"","type":"dissertation","venue":"TSpace","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Massachusetts Institute of Technology; Leukemia and Lymphoma Society; National Science Foundation","keywords":"Bioprocess; Embryoid body; Embryonic stem cell; Cell culture; Cell; Cellular differentiation; Microcarrier; Stem cell; Cell adhesion; Progenitor cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003624074,0.0004108977,0.0002718903,0.0003324829,0.0002004599,0.0005621502,0.0002830545,0.0003186745,0.001271017],"category_scores_gemma":[0.0002743966,0.0002451027,0.0004199616,0.0002993568,0.0001726497,0.0003503511,0.0002885833,0.0007568006,0.0006903342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003119578,"about_ca_system_score_gemma":0.0003547668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002321831,"about_ca_topic_score_gemma":0.0005791252,"domain_scores_codex":[0.9997398,0.00001739933,0.0000256676,0.00005294186,0.0001459614,0.00001815292],"domain_scores_gemma":[0.999862,0.00003391913,0.00004582016,0.00002079066,0.00002223627,0.00001525179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008481735,0.00001217278,0.00005702929,0.00004902019,0.000002367772,0.00002453328,0.00001664863,0.0001904016,0.996216,0.0001216531,0.00005832851,0.003243339],"study_design_scores_gemma":[0.000005126392,0.00007093211,0.000472387,0.00001163299,0.000007488949,0.00003261074,0.000009675001,0.001046698,0.9958811,0.00006045873,0.002396809,0.000005084674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7567785,0.0054421,0.2294598,0.0002910805,0.0002797686,0.0005233596,0.00126264,0.001171603,0.004791122],"genre_scores_gemma":[0.7769259,0.00731438,0.2041633,0.0001483161,0.00007045201,0.0007988305,0.001884706,0.0002898668,0.008404225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001271017,"threshold_uncertainty_score":0.004251957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360951994275945,"score_gpt":0.3100401247453643,"score_spread":0.2964306048026049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}