{"id":"W7133044397","doi":"","title":"BRCA1 in DNA Damage-induced Senescence and Sex Specific Outcomes following Repeated Mild Traumatic Brain Injury","year":2022,"lang":"","type":"dissertation","venue":"TSpace","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Senescence; DNA damage; DNA repair; DNA; Pathophysiology; Traumatic brain injury; Mechanism (biology)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002398931,0.0001591472,0.0001721794,0.0002602842,0.0002386586,0.000372242,0.0001342719,0.0002845415,0.004027526],"category_scores_gemma":[0.0002367928,0.00007874426,0.0001733725,0.0001581518,0.0001586939,0.0001407664,0.0002495728,0.0004345576,0.0006435117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002259638,"about_ca_system_score_gemma":0.0004987331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007546329,"about_ca_topic_score_gemma":0.001548511,"domain_scores_codex":[0.9999485,0.000007809683,0.000002418835,0.00001236828,0.00001351298,0.00001546178],"domain_scores_gemma":[0.9999063,0.000008254277,0.00002704605,0.000004102337,0.00001790846,0.00003638077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006258032,0.001250702,0.03034212,0.001258805,0.0001439805,0.001006603,0.001612006,0.0004429512,0.5948074,0.004757687,0.01214341,0.3459763],"study_design_scores_gemma":[0.0002146703,0.006271839,0.7221962,0.0008393324,0.0002853798,0.002127977,0.001796173,0.0006783819,0.1651487,0.004545855,0.09584165,0.00005384711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.925333,0.05432682,0.001167897,0.002504442,0.0003001563,0.00007164184,0.001144877,0.0000698873,0.01508134],"genre_scores_gemma":[0.9201206,0.03654047,0.0008882519,0.0005965926,0.0001492976,0.0001168978,0.0008478709,0.00002750614,0.04071251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004027526,"threshold_uncertainty_score":0.01347339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05252747252184715,"score_gpt":0.3701601486907987,"score_spread":0.3176326761689515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}