{"id":"W7133050085","doi":"","title":"Mapping Chromatin Composition of Transcription Factor Binding Sites in HEK293 Cells Using Histone Modifications","year":2025,"lang":"","type":"dissertation","venue":"TSpace","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Amgen (Canada)","funders":"","keywords":"Histone code; Chromatin; Histone; Histone H1; Transcription factor; Histone H2A; Epigenomics; Chromatin immunoprecipitation; Histone methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002085501,0.0001635902,0.0003948347,0.0005353466,0.0003073179,0.0006081727,0.0003057174,0.0002460224,0.002726706],"category_scores_gemma":[0.0003368944,0.0002156126,0.0004602412,0.001347617,0.0001399457,0.0002487871,0.0002156426,0.0003958223,0.002183704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003247119,"about_ca_system_score_gemma":0.0002500215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002973752,"about_ca_topic_score_gemma":0.00393592,"domain_scores_codex":[0.9997608,0.00001145527,0.00001909861,0.0001098277,0.00006959865,0.0000292177],"domain_scores_gemma":[0.9998339,0.00004919268,0.00002921909,0.0000386821,0.00003415224,0.00001477418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001976392,0.00001630758,0.009923124,0.0001148908,0.00004561243,0.00008870231,0.00006479043,0.0009861857,0.9744247,0.0003173587,0.0009799405,0.01284074],"study_design_scores_gemma":[0.00002259949,0.00009974081,0.1318587,0.0000158969,0.00007910212,0.0005816557,0.0001459577,0.01185237,0.8336536,0.0009255135,0.02072384,0.00004101326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7532054,0.001770163,0.0819729,0.0001696628,0.00006842946,0.00009180132,0.1532819,0.002641117,0.00679871],"genre_scores_gemma":[0.6410897,0.002619267,0.1057564,0.0002333791,0.00002608919,0.0002486846,0.2420975,0.0006652441,0.007263856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002973752,"threshold_uncertainty_score":0.009121716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02641603889670514,"score_gpt":0.3106441865897697,"score_spread":0.2842281476930646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}