{"id":"W7133052055","doi":"","title":"Data-driven Methods For Cancer Metabolism And Epigenetics","year":2019,"lang":"","type":"dissertation","venue":"TSpace","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Epigenetics; Myeloid leukemia; Isocitrate dehydrogenase; IDH1; Gene; Cancer; Downregulation and upregulation; Temozolomide; Genome instability","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02565594,0.002355352,0.002330721,0.004588642,0.001099364,0.00482421,0.004535838,0.002573568,0.009730815],"category_scores_gemma":[0.05866849,0.001527937,0.005903391,0.003919423,0.001857035,0.00361238,0.004727499,0.005726379,0.004936764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002224149,"about_ca_system_score_gemma":0.004430468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002857561,"about_ca_topic_score_gemma":0.0030074,"domain_scores_codex":[0.987778,0.006071083,0.001091388,0.001754285,0.003022181,0.0002829479],"domain_scores_gemma":[0.9636396,0.02520658,0.001409325,0.00486797,0.004387949,0.0004885423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.000672064,0.000330825,0.005166344,0.003089133,0.001799926,0.0006038797,0.0004386335,0.181191,0.005437253,0.2912662,0.0439992,0.4660056],"study_design_scores_gemma":[0.000137414,0.0000962397,0.0006082786,0.0002832266,0.0001816605,0.0002401553,0.0001316498,0.6271355,0.00346771,0.2887347,0.07890812,0.00007529932],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.0004541709,0.0007297008,0.9926886,0.0005779173,0.0002072106,0.0002470044,0.001176806,0.003041905,0.0008767223],"genre_scores_gemma":[0.01968158,0.00112039,0.9694718,0.0006347399,0.0002609202,0.001578302,0.004353977,0.001151773,0.001746544],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02565594,"threshold_uncertainty_score":0.1356832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0541560869179418,"score_gpt":0.4536139577800214,"score_spread":0.3994578708620796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}