{"id":"W7133058229","doi":"","title":"Investigations on an Alternative Approach to Fmoc Deprotection and Diversification of the Alumino-Mannich Reaction","year":2023,"lang":"","type":"dissertation","venue":"TSpace","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Diethylamine; Steric effects; Amine gas treating; Imine; Piperidine; Reagent; Sulfonyl; Aldimine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003962026,0.0004318107,0.0001900368,0.0001909571,0.000218609,0.0003827879,0.0003022366,0.0003101802,0.001836673],"category_scores_gemma":[0.0002395804,0.0001447393,0.0002372868,0.0001615064,0.0002111066,0.0004214077,0.0001945497,0.0007199782,0.0006775699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002608317,"about_ca_system_score_gemma":0.0003558672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000272854,"about_ca_topic_score_gemma":0.000423336,"domain_scores_codex":[0.9998201,0.00003095399,0.000009014921,0.00003709583,0.00005180659,0.00005099445],"domain_scores_gemma":[0.9999256,0.00001852926,0.00001848673,0.00001089999,0.00001648915,0.00001007792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000638923,0.00006246511,0.0001021004,0.0002418365,0.00001203324,0.0001507214,0.0001172319,0.0002363604,0.9870095,0.002225374,0.0001946103,0.009583924],"study_design_scores_gemma":[0.00001263656,0.0003116719,0.0004360186,0.00001609512,0.00001356739,0.0002435849,0.0000345691,0.0004777978,0.9863237,0.0001986539,0.01192098,0.00001084108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9360625,0.007763097,0.03542958,0.0003916189,0.0001160412,0.0003018049,0.0002423588,0.0001549418,0.01953821],"genre_scores_gemma":[0.933382,0.01074676,0.03696469,0.0002699444,0.00005421647,0.0002173566,0.0005818626,0.00008441252,0.01769878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001836673,"threshold_uncertainty_score":0.006144345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03031853736814655,"score_gpt":0.3077143663664563,"score_spread":0.2773958289983097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}