{"id":"W7133061874","doi":"","title":"The Role of Endothelial-Specific Intraflagellar Transport Protein 88 in Doxorubicin-Induced Cardiotoxicity","year":2020,"lang":"","type":"dissertation","venue":"TSpace","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto","keywords":"Intraflagellar transport; Cilium; Cardiotoxicity; Vacuolization; Contractility; Function (biology); Cardiomyopathy; Ciliopathy; Fibrosis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009515632,0.0001431139,0.00008292133,0.0001246657,0.0001206256,0.0001344287,0.00008339196,0.0002153509,0.000921172],"category_scores_gemma":[0.00007114128,0.00006274477,0.0001291609,0.00005670212,0.0001142779,0.0001114544,0.0001201024,0.0003032728,0.0002058213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002206377,"about_ca_system_score_gemma":0.0001993663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003577927,"about_ca_topic_score_gemma":0.0006159921,"domain_scores_codex":[0.9999713,0.000004497208,0.00000219862,0.000006065429,0.000005944268,0.00001009092],"domain_scores_gemma":[0.999961,0.000003432169,0.00001291908,0.000002463475,0.000008072711,0.00001209161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002778016,0.00004621064,0.001022959,0.0000930867,0.00000682694,0.0001626281,0.00002359288,0.00008984389,0.9888949,0.0004998713,0.0002393474,0.008642808],"study_design_scores_gemma":[0.00005781672,0.0008970175,0.1266306,0.00009543754,0.00006754793,0.001334381,0.0001267256,0.001497766,0.8548785,0.000441726,0.01396047,0.00001207928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795696,0.01148885,0.002961319,0.0006256077,0.00004553258,0.0000322122,0.0003175416,0.00003756354,0.004921619],"genre_scores_gemma":[0.9813237,0.007679971,0.001516995,0.0001364749,0.00001238149,0.00003302261,0.0003547039,0.000009122178,0.008933612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000921172,"threshold_uncertainty_score":0.00308156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007631953216934603,"score_gpt":0.2537719070466936,"score_spread":0.246139953829759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}