{"id":"W7134097773","doi":"","title":"Additional file 1 of Long-term efficacy and safety of sapropterin in patients who initiated sapropterin at < 4 years of age with phenylketonuria: results of the 3-year extension of the SPARK open-label, multicentre, randomised phase IIIb trial","year":2021,"lang":"","type":"article","venue":"Open MIND","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Extension (predicate logic); SPARK (programming language); Table (database); Quarter (Canadian coin)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002467356,0.001159413,0.001767445,0.0008971633,0.0007760837,0.00120104,0.001225034,0.00128659,0.764605],"category_scores_gemma":[0.02615929,0.0005548553,0.00118989,0.001764594,0.0002861496,0.001779532,0.0006414616,0.001200175,0.05834542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009195536,"about_ca_system_score_gemma":0.001680192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002616138,"about_ca_topic_score_gemma":0.005555749,"domain_scores_codex":[0.9989662,0.0003085675,0.0002309369,0.0001672934,0.000173144,0.0001538908],"domain_scores_gemma":[0.9821011,0.01205847,0.002781659,0.0009146181,0.001560189,0.0005838976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.01892573,0.000728375,0.004407493,0.01275337,0.0004872781,0.0001525217,0.00009633751,0.0009933693,0.0002339867,0.001658818,0.9323001,0.02726248],"study_design_scores_gemma":[0.3799003,0.009656867,0.08980405,0.01488488,0.002904758,0.001625336,0.0004800128,0.005919908,0.002044708,0.02374686,0.468659,0.0003734705],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.001564004,0.0001366825,0.0004663579,0.0003944893,0.00005579617,0.001337902,0.9930888,0.0002001548,0.002755825],"genre_scores_gemma":[0.07866692,0.0009004291,0.008875846,0.00281786,0.0006752851,0.03538637,0.8348192,0.0005494911,0.0373087],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.764605,"threshold_uncertainty_score":0.3357624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02658768103721881,"score_gpt":0.2842899624171704,"score_spread":0.2577022813799516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}