{"id":"W7135100218","doi":"10.5376/cge.2024.12.0013","title":"Mechanisms of Interaction Between Epigenetic Modifications and Cancer Genomics","year":2024,"lang":"","type":"article","venue":"Cancer Genetics and Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Epigenetics; Cancer; Genomics; Mechanism (biology); Disease; Genome","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004284893,0.0006913095,0.0006756553,0.0003033053,0.0002728007,0.0002764218,0.0003265048,0.0007260661,0.00007485293],"category_scores_gemma":[0.00004152548,0.0007671551,0.0002075359,0.0003905437,0.0005226317,0.0000158216,0.00041805,0.0003765282,0.000004823721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001225029,"about_ca_system_score_gemma":0.0006793232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002513772,"about_ca_topic_score_gemma":0.0001926196,"domain_scores_codex":[0.9962599,0.0001651317,0.00118776,0.001355404,0.0003601966,0.00067161],"domain_scores_gemma":[0.9979426,0.0001152386,0.0003756542,0.0007266158,0.0003820582,0.0004578221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000519894,0.00008059,0.009115181,0.001168972,0.0008360337,0.000003186033,0.0008319431,0.005713301,0.5497225,0.001226883,0.00009712483,0.4311523],"study_design_scores_gemma":[0.0007523931,0.0009636495,0.02426373,0.0006422627,0.001683302,0.000007049757,0.0004083033,0.02291515,0.8157941,0.01010761,0.1210792,0.001383279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.557107,0.3935813,0.04585258,0.0004609599,0.001259892,0.0005529085,0.0009113167,0.00001690061,0.0002571299],"genre_scores_gemma":[0.5992588,0.3976814,0.001912285,0.00004069046,0.0005403531,0.00008176828,0.00008954897,0.0001046261,0.0002904881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.429769,"threshold_uncertainty_score":0.9994779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03138731254150361,"score_gpt":0.3201064777857892,"score_spread":0.2887191652442856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}