{"id":"W7140064968","doi":"","title":"Des lipopeptides synthétiques dérivés des domaines intracellulaires de récepteurs à 7 TM comme outils de découverte et de thérapie : nouvelles orientations","year":2025,"lang":"en","type":"other","venue":"Open MIND","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Faculty of Medicine and Health, University of Sydney; Région Normandie; Réseau québécois de recherche sur la douleur; Université de Sherbrooke; European Commission; Canadian Institutes of Health Research; Québec Consortium for Drug Discovery","keywords":"Receptor; Signalling; Transmembrane protein; Drug discovery; Biotinylation; G protein-coupled receptor; Drug; Signal transduction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004924255,0.000423385,0.0003140153,0.0002750842,0.0001664154,0.0005915578,0.0001937362,0.0003926535,0.001616534],"category_scores_gemma":[0.0003964423,0.000141983,0.0004205455,0.000132407,0.0004211246,0.0005863598,0.0003203343,0.0009677786,0.0008368503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004252832,"about_ca_system_score_gemma":0.0003160163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002538392,"about_ca_topic_score_gemma":0.0002308967,"domain_scores_codex":[0.9998124,0.00005051073,0.00001780736,0.00003218677,0.0000582265,0.00002890335],"domain_scores_gemma":[0.9998847,0.00003317582,0.00002392881,0.00001318767,0.00002317336,0.00002183385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009519552,0.0001541311,0.0003745244,0.0005113172,0.00003318756,0.000427576,0.0001421334,0.0006432887,0.9398218,0.004836567,0.0008330763,0.05127053],"study_design_scores_gemma":[0.0001744798,0.001510742,0.001129225,0.00008365711,0.00006401685,0.000801782,0.00005493687,0.0009564467,0.94206,0.0007224667,0.05240798,0.00003431981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8386631,0.07689742,0.05817163,0.002684936,0.001880147,0.0005157811,0.0008658025,0.000303614,0.02001747],"genre_scores_gemma":[0.8849559,0.05565574,0.03063722,0.001250705,0.0005918089,0.000435446,0.00134231,0.0001254935,0.02500523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001616534,"threshold_uncertainty_score":0.00540787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05022178397229239,"score_gpt":0.36131566447048,"score_spread":0.3110938804981876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}